Enhancing vaccination of key populations: Lessons and actions
Jinsong Zhang1, Zaihong Li2, Jiahai Lu3, Zeliang Chen4
1 One Health Centerof Excellence for Research and Training, School of Public Health; NMPA Key Laboratory for Quality Monitoring and Evaluation of Vaccines and Biological Products; Key Laboratory of Tropical Diseases Control, Sun Yat-Sen University, Ministry of Education, Guangzhou 510080, China 2 Hainan Women and Children's Medical Center (Women and Children's Health Care Center of Hainan Province, Hainan Children's Hospital,Children's Hospital of Fudan University at Hainan, Hainan Obstetrics and Gynecology Hospital), Haikou 571100, China 3 One Health Centerof Excellence for Research and Training, School of Public Health; NMPA Key Laboratory for Quality Monitoring and Evaluation of Vaccines and Biological Products; Key Laboratory of Tropical Diseases Control, Sun Yat-Sen University, Ministry of Education, Guangzhou 510080; Research Institute of Sun Yat-Sen University in Shenzhen, Shenzhen 518057; Hainan Key Novel Thinktank “Hainan Medical University ‘One Health’ Research Center”, Haikou 571199, China 4 One Health Centerof Excellence for Research and Training, School of Public Health; NMPA Key Laboratory for Quality Monitoring and Evaluation of Vaccines and Biological Products; Key Laboratory of Tropical Diseases Control, Sun Yat-Sen University, Ministry of Education, Guangzhou 510080; Key Laboratory of Zoonose Prevention and Control at Universities of Inner Mongolia Autonomous Region, Medical College, Inner Mongolia Minzu University, Tongliao 028000, China
Correspondence Address:
Jiahai Lu One Health Centerof Excellence for Research and Training, School of Public Health; NMPA Key Laboratory for Quality Monitoring and Evaluation of Vaccines and Biological Products; Key Laboratory of Tropical Diseases Control, Sun Yat-Sen University, Ministry of Education, Guangzhou 510080; Research Institute of Sun Yat-Sen University in Shenzhen, Shenzhen 518057; Hainan Key Novel Thinktank “Hainan Medical University ‘One Health’ Research Center”, Haikou 571199 China Zeliang Chen One Health Centerof Excellence for Research and Training, School of Public Health; NMPA Key Laboratory for Quality Monitoring and Evaluation of Vaccines and Biological Products; Key Laboratory of Tropical Diseases Control, Sun Yat-Sen University, Ministry of Education, Guangzhou 510080; Key Laboratory of Zoonose Prevention and Control at Universities of Inner Mongolia Autonomous Region, Medical College, Inner Mongolia Minzu University, Tongliao 028000 China
 Source of Support: This work was funded by the State Key Program of National Natural Science of China (U1808202), NSFC International (regional) cooperation and exchange program (31961143024), the Key Program of Inner Mongolia (2019ZD006), Conflict of Interest: None
DOI: 10.4103/2773-0344.361972
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Vaccination is effective in preventing the increase of disease, especially emerging infectious diseases (EIDs), and it is particularly important for people in close contact with infected sources and susceptible populations who are at increased risk of getting infectious diseases due to behavior, occupation or health. Despite targeted vaccination guidelines, inadequate vaccination of the key populations fails to receive widespread attention, resulting in a high-risk transition of disease from key populations to general populations. Strengthening the vaccination of the susceptible groups can effectively block the spread of pathogens to general populations, and reduce the consumption of medical resources in universal vaccination, which has significant economic value. In this review, we describe the prevalence of EIDs, analyze the experience and lessons of infectious disease vaccination in key populations through several cases, and further explore the causes for the decline in vaccination rates of key populations. According to the trends of EIDs, a plan to strengthen the vaccination of key populations is proposed to effectively prevent the transition of EIDs from key populations to general populations.
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